Adjunct Assistant Professor
Department of Biological Sciences, National University of Singapore


Ph.D. in Biology, Massachusetts Institute of Technology, U.S.A.
Advisor: Robert Langer, Sc.D., David H. Koch Institute Professor, MIT
& Omid Farokhzad, M.D., Associate Professor of Anesthesiology, Harvard Medical School
Dissertation: Spatiotemporal Controlled Delivery of Nanoparticles to Injured Vasculature.


B.A., M.A., double First Class Honors in Biochemistry and Molecular Biology,
Christ’s College, Cambridge University, U.K.
Advisor: Richard J. Jackson, Ph.D., Department of Biochemistry, Cambridge University
Dissertation: Reinitiation of Eukaryotic mRNA Translation After Puromycin-induced Termination.

[20] Fellow, ACS Nano Junior Fellowship, 2017

[19] Young Global Leader of the World Economic Forum, Class of 2015

[18] Recipient, Singapore50 Celebration Fund Grant, 2015

[17] Science and Technology (STS) Forum 2015 Future Leaders Program (10 junior faculty around the world)

[16] MIT Technology Review TR35’s 10 Innovators Under 35 (Asia) 2014

[15] Prestige Singapore Forty Under 40 list 2013

[14] Recipient, 30th World Cultural Council Special Recognition Award (S$5,000 research grant)

[13] Recipient, Singapore Youth Award 2013 (S$8,000 community project grant)

[12] Recipient, Nanyang Assistant Professorship 2013 (S$1 million start-up grant)

[11] Winner, Junior Chamber International Singapore (JCI) Ten Outstanding Young Persons Of The Year 2013

[10] Winner, 2011-2012 L’Oréal-UNESCO For Women in Science (FWIS) National Fellowships (Singapore) (S$30,000 fellowship grant)

[9] Winner, Singapore Women’s Weekly Great Women of Our Time Award, 2010 (Science & Technology category)

[8] Honorary Fellow, Cambridge Commonwealth Trust, Cambridge University

[7] Christ College Scholar, Cambridge University

[6] S. W. Greig Prize for Natural Sciences Part II, 2005, Cambridge University

[5] 2005 College Prize (Christ’s College, Cambridge University)

[4] S. W. Greig Prize for Natural Sciences Part IB, 2004, Cambridge University

[3] 2004 College Prize (Christ’s College, Cambridge University)

[2] Sir Hans Kornberg Travel Award for Research, 2004, Cambridge University

[1] Agency for Science, Technology and Research, Singapore B.S.-Ph.D. National Science Fellowship

[3] Chan JM and Xu C. Perspectives in Micro- and Nanotechnology for Biomedical Applications. Imperial College Press (2016).
[2] Chan JM, Sim S and Tan R. Bugs & Quarks. Asian Scientist (2016). [website]
[1] Chan JM, Chua G, Sim S and Tan R. Singapore’s Scientific Pioneers. Asian Scientist (2015). [website]
Highlighted in The Singapore Straits Times



[22] Krishnamurthy S, Muthukumaran P, Jayakumar MKG, Lisse D, Masurkar ND, Xu C, Chan JM and Drum CL. Surface protein engineering increases the circulation time of a cell membrane-based nanotherapeutic. Nanomedicine (2019) [website]

[21] Deshpande S, Masurkar N, Mavelli GV, Desai M, Chakraborty G, Chan JM and Drum CL. Thermostable exoshells fold and stabilize recombinant proteins. Nature Communications (2017) [website]
Highlighted in The Singapore Straits Times
[20] Muller P, Chan JM, Simoncik O, Fojta M, Lane DP, Hupp T and Vojtesek B. Evidence for allosteric effects on p53 oligomerization induced by phosphorylation. Protein Science (2017) E-pub before print. [website]
[19] Ho SH, Yang X, Thanwarani A and Chan JM. Examining public acquisition of science knowledge from social media in Singapore: an extension of the cognitive mediation model. Asian Journal of Communication (2016) E-pub before print. [website]
[18] Krishnamurthy S, Gnanasammandhan MK, Xie C, Huang K, Cui MY and Chan JM. Monocyte Cell Membrane-derived Nanoghosts for Targeted Cancer Therapy. Nanoscale (2016) 8:6981-5. [pdf]
[17] Ho SS, Yang X, Thanwarani A and Chan JM. Acquiring science knowledge from social media: An extension of the cognitive mediation model. Annual meeting of International Communication Association (Communication & Technology Division), Fukuoka, Japan (2016).
[16] Ho SS, Yang X, Liao Y, Turner D, Tan R and Chan JM. A Survey of Public Views and Attitudes Towards Science and Technology Issues in Singapore. Asian Scientist (2015). [pdf]
Highlighted in The Singapore Straits Times
[15] Krishnamurthy S, Chan JM. Lipid-polymer hybrid nanoparticles for drug delivery applications. Sigma-Aldrich Drug Delivery Handbook (2015). [pdf]
[14] Chan JM, Wong KHK, Richards AM, Drum CL. Microengineering in cardiovascular research: new developments and translational applications. Cardiovascular Research (2015) 1;106(1):9-18. [pdf]
[13] Krishnamurthy S, Vaiyapuri R, Zhang L, Chan JM. Lipid-coated polymeric nanoparticles for cancer drug delivery. Biomaterials Science (2015) 3: 923-936. [pdf]
[12] Chan JM, Zervantonakis IK, Rimchala T, Polacheck WT, Whisler J, Kamm RD. Engineering of in vitro 3D capillary beds by self-directed angiogenic sprouting. PLoS ONE (2012) 7(12): e50582. [pdf]
Highlighted in Lab on a Chip
[11] Xiao Z, Levy-Nissenbaum E, Alexis F, Lupták A, Teply BA, Chan JM, Shi J, Digga E, Cheng J, Langer R, Farokhzad OC. Engineering of Targeted Nanoparticles for Cancer Therapy Using Internalizing Aptamers Isolated by Cell-Uptake Selection. ACS Nano (2012) 6(1):696-704. [pdf]
[10] Wong K, Chan JM, Kamm RD, Tien J. Microfluidic Models of Vascular Functions. Annual Review in Biomedical Engineering (2012) 14:205-30. [pdf]
[9] Chan JM, Rhee JW, Drum CL, Bronson RT, Golomb G, Langer R, Farokhzad OC. In vivo prevention of arterial restenosis with paclitaxel-encapsulated targeted lipid-polymeric nanoparticles. Proc Natl Acad Sci U S A (2011) 108(48):19347-52. [pdf]
[8] Gao W, Chan JM, Farokhzad OC. pH-responsive nanoparticles for drug delivery. Mol Pharm (2010) 7(6):1913-20. [pdf]
[7] Chan JM, Zhang L, Tong R, Ghosh D, Gao W, et al. Spatiotemporal Controlled Delivery of Nanoparticles to Vasculature. Proc Natl Acad Sci U S A. (2010) 107(5):2213-8. [pdf]
Highlighted in BBC Health
Highlighted in The Independent
Highlighted in Science Daily
Highlighted in Medical News Today
Highlighted in Nano Today
Highlighted in The Singapore Straits Times

[6] Chan JM, Valencia PM, Zhang L, Langer R, Farokhzad OC. Polymeric nanoparticles for drug delivery. Methods Mol Biol. (2009) 624:163-75. [pdf]
[5] Chan JM, Zhang L, Yuet KP, Liao G, Rhee JW, Langer R, et al. PLGA-lecithin-PEG core-shell nanoparticles for controlled drug delivery Biomaterials. (2009) 30(8):1627-34. [pdf]
[4] Nguyen DN, Green JJ, Chan JM, Langer R, Anderson DG. Polymeric Materials for Gene Delivery and DNA Vaccination. Advanced Materials. (2009) 21(8):847-67. [pdf]
[3] Zhang L, Chan JM, Gu FX, Rhee J-W, Wang AZ, et al. Self-Assembled Lipid-Polymer Hybrid Nanoparticles: A Robust Drug Delivery Platform. ACS Nano. (2008) 2(8):1696-702. [pdf]
[2] Wang AZ, Gu F, Zhang L, Chan JM et al. Biofunctionalized targeted nanoparticles for therapeutic applications. Expert Opin Biol Ther. (2008) 8(8):1063-70. [pdf]
[1] Zhang L, Gu FX, Chan JM, Wang AZ, Langer RS, Farokhzad OC. Nanoparticles in medicine: therapeutic applications and developments. Clin Pharmacol Ther. (2008) 83(5):761-9. [pdf]


[4] Farokhzad OC, Salvador-Morales C, Gao W, Zhang L, Chan JM, Langer RS. Particles with multiple functionalized surface domains. Patent Publication No.: 9649391


[3] Farokhzad OC, Salvador-Morales C, Gao W, Zhang L, Chan JM, Langer RS. Particles with multiple functionalized surface domains. Patent Publication No.: US 2012/0156135 Patent licensed to Blend Therapeutics, Cambridge, MA.

[2] Alexis F, Zhang L, Chan J, Basto P, Levy-Nissembaum E, Langer R, Farokhzad OC. Poly (Amino Acid)-Targeted Drug Delivery. Patent Publication No.: US 2009/0074828 Patent licensed to Selecta Biosciences and BIND Therapeutics, Cambridge, MA.

[1] Chan JM, Langer R, Farokhzad OC. Endothelial Basement Membrane Targeting Peptide Ligands for Nanoparticle Delivery of Therapeutic Agents. Patent Publication No.: US 2011/0143993